Anti-depressant Activity of the Seeds of Zanthoxylum armatum on Swiss Albino Mice

Introduction: Depression disorder has significant potential morbidity and mortality, contributing to suicide, incidence adverse outcomes of medical illness, disruption in interpersonal relationships, substance abuse, lost work time. Objectives: The present study was designed the anti-depressant activity seeds extract Zanthoxylum armatum using a forced swim test tail suspension on Swiss albino mice. assessed Chronic Unpredictable Mild-Stress (CUMS) induced depression Methods: animals were treated with methanolic orally at two doses 100, 200mg/kg body weight for eight days after CUMS results demonstrate that Methanolic got potential. Results: showed had antidepressant activity. Microsoft Excel used calculate mean ± SEM one-way ANOVA followed by turkey multiple comparison analyze results. seed presented mice (p<0.05). Conclusions: This conducted explore extracts plant